Magnesium threonate benefits include reducing inflammation and helping to treat ADHD. It also improves executive function. Taking it can even help prevent memory deficits associated with chronic neuropathic pain.
Reduces inflammation
Magnesium L-threonate (MgT) is a safe and effective supplement for reducing inflammation in the brain and preventing neurodegenerative diseases. It is also used as a migraine treatment. In a study, it was found to reduce inflammation and inflammatory cytokines in the colon.
The effects of magnesium on the human body are varied, but one of its most important roles is to regulate the stress response. Several studies have shown that magnesium helps prevent excessive excitation of neurons. Moreover, it has been shown to enhance learning and memory in rats. This has led researchers to consider MgT as a food supplement for preventing memory impairments induced by alcohol abuse.
Another study shows that MgT can be used to reduce inflammation in the gut-brain axis of mice. In addition, it has been shown to reduce anxiety and concentration problems in the study participants.
Moreover, it has been shown that increasing brain magnesium levels promotes synaptic plasticity in the prefrontal cortex, and it is associated with increased self-renewal of neural stem cells. Additionally, it is associated with an increased density of presynaptic puncta. Similarly, it is thought that the ability of the blood-brain barrier to absorb MgT might be responsible for the therapeutic effect.
It is believed that the increased presence of circulating magnesium in the blood is linked to the reduced risk of cardiovascular disease. Increasing intake of this mineral has been shown to lower the incidence of CHD in men and women. However, there has not been any evidence that it prevents the formation of atherosclerotic plaques.
A recent study has shown that magnesium L-threonate reduces the effects of oxaliplatin on synaptic changes in the brain. It has been shown to be safe for use in patients with Parkinson’s disease.
Improves executive function
Magnesium threonate is a dietary supplement that may help improve your executive function. It can also improve your memory, sleep, and reduce anxiety.
In a study, older adults who took a supplement of magnesium l-threonate showed a dramatic decrease in their brain age. Researchers found that the participants’ collective brain age had decreased by nearly nine years.
Another study showed that the participants’ short-term memory and spatial memory improved. They also reported a reduction in the amount of stress they felt while completing cognitive tasks.
The magnesium threonate study also found that the participants’ executive function improved significantly. Executive functioning is the ability to plan and perform tasks. Normally, this function declines as we get older. However, the magnesium threonate study showed that the participants’ executive function was restored to a near-normal level for their age.
Other studies have shown that the brain can be protected from hypoxic injuries. Additionally, magnesium has been shown to improve cognitive function and increase mental processing speed.
Research has shown that ginkgo biloba supplements can boost the brain’s circulation and repair damaged synapses. A study in rats revealed that it improved spatial memory.
A separate study conducted by Tsinghua University in China found that the participants had less stress while performing cognitive tasks. Cognitive tests were taken in six-week increments. The participants’ scores on these tests improved by five to 12%.
Magnesium L-threonate has been proven to support cognitive abilities in both healthy individuals and those with neurological conditions such as ADHD. This treatment is safe to use, and it has been shown to increase cognitive function, prevent brain cell death, and stimulate new brain cells in memory-related areas of the brain.
The subjects in the magnesium threonate study were given a daily dosage of between 1.5 and 2 mg. They were also given a supplement containing Magtein.
Helps treat ADHD
Magnesium is an important mineral in the human body. It is involved in over 600 metabolic reactions in the body, including protein formation, energy production, and blood pressure regulation. It also plays a key role in the conversion of essential fatty acids to long-chain omega-3 and omega-6 fatty acids.
Deficiency in magnesium can lead to problems in the brain. This includes trouble concentrating, sleep disorders, and irregular heartbeat. The effects of magnesium deficiency have also been shown to reduce anxiety, which can manifest itself in the form of depressive symptoms.
Although it is a common supplement, magnesium is not included in most modern diets. In fact, less than half of the US population is getting the recommended daily amount of this mineral.
Taking magnesium can improve many ADHD symptoms. One study found that magnesium supplementation increased attention span, reduced hyperactivity, and improved inattention. Another study found that magnesium L-threonate improved cognitive function, concentration, and mental health in ADHD patients.
ADHD is a neurodevelopmental disorder characterized by inattention and difficulty controlling behavior. Children with the condition are more likely to develop other disorders. Therefore, treatment is important. Taking magnesium is a safe and effective way to help children with ADHD.
ADHD affects about 5% of school-aged children. There are several risk factors for the disorder, including low birth weight, preterm delivery, maternal stress during pregnancy, smoking, substance abuse, and environmental contaminants. Many parents seek alternative therapies to help their children.
Magnesium and vitamin D are known to help improve the physical and mental health of children with ADHD. Studies have also found that magnesium is safe and well-tolerated.
Research suggests that the supplementation of magnesium and vitamin D can help to reduce behavioral problems in children with ADHD. However, a larger trial is needed to determine the true effect of the supplements.
Prevents memory deficits associated with chronic neuropathic pain
Neuropathic pain is a condition that causes pain, numbness, and burning. It can be caused by damage to the peripheral nervous system or the central nervous system. In patients suffering from chronic neuropathic pain, memory deficits may be present.
In neuropathic pain, the CCR2 receptor plays an important role. The receptor is expressed by resident microglia in the bone marrow. When it is damaged, it increases sodium channels and firing of first order neurons. Pain is experienced because of ectopic discharges in the fibers, which result from enhanced depolarization at certain sites. Some symptoms include numbness, burning, and pins and needles.
Patients with fibromyalgia and neuropathic pain show similar clinical features. Both disorders share the same pathophysiological processes. This includes the release of TNF-a in the blood, which is increased in patients with fibromyalgia.
Although the role of TNF-a in neuropathic pain has not been determined, it is thought that it is a neuronal disruptor. Chronic neuropathic pain may be induced by peripheral nerve injury, and the resulting damage may contribute to memory deficits.
To prevent memory deficits associated with neuropathic pain, scientists have found that targeting TNF-a may be helpful. A drug that targets this molecule, called thalidomide, decreases endoneurial tumor necrosis factor-alpha. Similarly, an anti-TNF-alpha drug called lornoxicam has also been tested for its effectiveness.
Researchers have shown that patients with fibromyalgia and chronic pain usually have memory deficits. These memory deficits are associated with reduced ability to process short-term information and solve problems. They are also characterized by poor mood and focus.
Studies in animals are being conducted to determine the role of neuropathic pain in the development of these memory deficits. An animal model has been established to demonstrate how peripheral nerve injury and central sensitization can affect cognitive function.
Reduces expression of a gene that’s involved in androgenic hair loss
Were you aware that there are multiple genes that are responsible for androgenic hair loss, and a recent study showed that the Androgen receptor (AR) is one of them. Interestingly, this gene was found to be overexpressed in the balding follicle, where its inverse was found in the beard-prone epidermis. The gene is a good model for the cellular amplification of androgen in the hair follicle, and it may also provide clues to a causal link between androgen and other follicular factors.
In a related study, a team of researchers discovered that a gene, PPARGC1A, was overexpressed in the epithelial papilla of miniaturized hair. This might explain why balding DP cells display more of the aforementioned aforementioned retinoid-like properties. On the other hand, a triumvirate of proteins, including TGFB1, TGFB1I1 and H2AX, were found to be overexpressed in the aforementioned bald follicles, thereby enhancing their androgen sensitivities. A similar trio was found in occipital scalp dermal papilla.
There are more eponymous genes involved in the hair follicle, including NPAR, which was shown to be a more important contributor to miniaturization than EGR1, although the two proteins are still thought to be independent. Nevertheless, androgens have been suggested to be the nascent triggers for miniaturization, and the PPAR pathway appears to play a central role in hair miniaturization.
